Esophagus & Stomach 02

This shows a portion of the mucosa and submucosa of the fundic stomach. Note the relatively-large blood vessels in the submucosa (Sb) and the well-defined muscularis mucosa, at M. The clusters of cells at the bases of the mucosal (or fundic) glands - such as the groups just above C - are chief cells. Their seromucous granules are distinctive because, although they are mostly solubilized (like other mucus-rich granules) and thus appear pale, they have enough protein to retain a distinct shape after the processing, so they remain as very distinct small pale granules. What is the round, eosinophilic cell just to the left of the P and why is its peripheral cytoplasm so obviously more heavily stained than the cytoplasm immediately around the nucleus? (Answers at bottom of frame).

Slide O-2, field O26/P26 of finder slide B, 16X objective